The Usual Treatments Not Effective Fighting Mesothelioma
Cancer doctors determine what kind of treatment to prescribe with each patient. There are numerous options. There are no regular treatment regimen for pleural mesothelioma sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.
While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Treatments for cancer are traditionally surgery (taking out the tumor and surrounding tissue), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) Each one of these methods have problems. Patients with mesothelioma have not responded well to traditional radiation therapy. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
The mesothelial tissue around the tumor is removed by surgery. The surgery is difficult and challenging, with unknown effects or benefits to patients. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and combinations of chemotherapy agents have been tried, but without much success. As with radiation, research is going toward controlling the physical location of the treatment with emphasis on the pleural cavity.
The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
